Fabrice Luchini was born in Île-de-France, Paris, into an Italian immigrant family, who were fruit and vegetable vendors. He grew up around the neighbourhood of Goutte d'Or in Paris's 18th arrondissement. When he was 13, his mother apprenticed him to a hairdresser in a trendy parlor on Avenue Matignon, where he would take the name of the hairdresser's son, Fabrice, in place of his real name, Robert. At the same time he developed a great interest for literature (Balzac, Flaubert, Proust). His passion for soul music (James Brown) made him a regular of discothèques. This is where he met Philippe Labro, who gave him his first role in Tout peut arriver in 1969. He then studied acting under Jean-Laurent Cochet. However, it was his collaboration with Éric Rohmer that would make him popular for Le Genou de Claire in 1970, in which he played a small role as an adolescent. He appeared in Rohmer's Perceval le Gallois, and Les Nuits de la pleine lune, and in films directed by Nagisa Oshima, Pierre Zucca, Claude Lelouch, Cedric Klapisch, Édouard Molinaro.
Thanks to Jean-Laurent Cochet, he later discovered theater, his true passion, which he described as "the only place where life is expressed... something that no school will ever teach". However, it was his role in La Discrète, directed by Christian Vincent in 1990, that made him well-known to the general public. He divides his work between cinema and theater, where since 1980 he has had considerable success with readings from the texts of La Fontaine, Nietzsche, Céline's Voyage au bout de la nuit, Paul Valéry and Roland Barthes.
| 2026 | Demain, je tombe amoureux as Émile |
| 2026 | Victor comme tout le monde as Robert Zuchini |
| 2025 | Laïcité, l'exception française - 120 ans, et maintenant ? as Self |
| 2025 | Natacha (presque) hôtesse de l'air as Narrator |
| 2025 | Le Secret de Khéops as Christian |
| 2024 | La Fontaine et le Confinement |
| 2024 | Marcello Mio as Fabrice |
| 2024 | Céline Dion, la bande originale de sa vie as Self - Guest |
| 2024 | İmparatorluk as Belzébuth |
| 2023 | La Petite as Joseph |
| 2023 | Suç Bende as Judge Gustave Rabusset |
| 2023 | Un homme heureux as Jean Leroy |
| 2022 | Par cœurs as Self |
| 2022 | Fabrice Luchini : des écrivains parlent d'argent |
| 2020 | Le Fantôme de Laurent Terzieff as Self (archive footage) |
| 2019 | Le Meilleur reste à venir as Arthur Dreyfus |
| 2019 | Jeanne as Roi Charles VII |
| 2019 | Les Trésors de Marcel Pagnol as Narrator (voice) |
| 2019 | Alice ve Belediye Başkanı as Paul Theraneau |
| 2019 | Henri Pick'in Gizemi as Jean Michel Rouche |
| 2018 | İmparator: Yeraltı Dünyasının Hükümdarı as Fouché |
| 2018 | Acelesi Olan Adam as Alain |
| 2016 | Sığ Sular as André van Peteghem |
| 2015 | L'Hermine as Michel Racine |
| 2015 | Un début prometteur as Francis Vauvel |
| 2014 | Les Enfoirés - Les Enfoirés en chœur de 1985 à aujourd'hui |
| 2014 | Visite à Hokusai as Narrator |
| 2014 | Aşkın Dili as Martin |
| 2013 | Alceste à bicyclette as Serge Tanneur |
| 2012 | Luchini - Variations La Fontaine as Self |
| 2012 | Asteriks ve Oburiks Gizli Görevde as Jules César |
| 2012 | Evde as Germain |
| 2011 | Les Femmes du 6e étage as Jean-Louis Joubert |
| 2010 | Kadın İsterse as Robert Pujol |
| 2010 | Les Invités de mon père as Arnaud |
| 2008 | Musée haut, musée bas as Guard at the Malraux museum |
| 2008 | Le Point sur Robert as Fabrice Luchini |
| 2008 | Stéphane Guillon - Portraits au vitriol (1ère salve) as Self |
| 2008 | La Fille de Monaco as Bertrand Beauvois |
| 2008 | Paris as Roland Verneuil |
| 2007 | Molière as M. Jourdain |
| 2006 | Jean-Philippe as Fabrice / Self |
| 2005 | La cloche a sonné as Simon Arcos |
| 2004 | Knock, ou le triomphe de la médecine as Doctor Knock |
| 2004 | Confidences trop intimes as William |
| 2003 | Le Coût de la vie as Brett |
| 2002 | Un jour dans la vie du cinéma français as Self |
| 2001 | Barnie et ses petites contrariétés as Barnie |
| 1999 | Pas de scandale as Grégoire Jeancourt |
| 1999 | Rien sur Robert as Didier Temple |
| 1999 | Les Enfoirés 1999 - Dernière édition avant l'an 2000 |
| 1998 | « Art » as Serge |
| 1998 | Par cœur as Self |
| 1997 | Le Bossu as Count Gonzague |
| 1997 | Un air si pur... as Magnus |
| 1996 | Erkekler Kadınlar ve Kullanma Kılavuzu as Fabio Lini |
| 1996 | Beaumarchais, l'insolent as Pierre-Augustin Caron de Beaumarchais |
| 1995 | L'Année Juliette as Camille Prader |
| 1994 | Le Colonel Chabert as Derville |
| 1993 | Tout ça… pour ça ! as Fabrice Lenormand |
| 1993 | Toxic Affair as The Analyst |
| 1993 | Ağaç, Belediye Başkanı ve Kültür Merkezi as Marc Rossignol, l’instituteur |
| 1992 | Riens du tout as Lepetit |
| 1992 | Le retour de Casanova as Camille |
| 1990 | Uranus as Jourdan |
| 1990 | La Discrète as Antoine |
| 1990 | Voyage au bout de la nuit as Self |
| 1990 | Six crimes sans assassins as Simon |
| 1988 | La Couleur du vent as Serge |
| 1988 | La Fée Carabine as Pastor |
| 1988 | Alouette, je te plumerai as Jacques |
| 1987 | Les Oreilles entre les dents as Luc Fabri |
| 1987 | Reinette ve Mirabelle'in Dört Macerası as Le marchand de tableau |
| 1986 | Max mon amour as Nicolas |
| 1986 | Hôtel du Paradis as Arthur |
| 1986 | Conseil de famille as Shady Lawyer |
| 1986 | Triple sec |
| 1985 | P.R.O.F.S. as Michel |
| 1985 | Rouge-gorge as Frédéric |
| 1984 | Dolunay Geceleri as Octave |
| 1984 | Emmanuelle 4 as Oswaldo |
| 1983 | Lettre de la Sierra Morena as Don Quichotte |
| 1983 | Zig Zag Story as Bob Hemler |
| 1983 | Il ne faut jurer de rien |
| 1982 | T'es folle ou quoi ? as Jean-François Sevran |
| 1981 | Droit de Réponse as Self |
| 1981 | Le Beau Monde as Jean-Pierre Davier |
| 1981 | La Femme de l'aviateur as Mercillat |
| 1980 | Même les mômes ont du vague à l'âme as Arthur |
| 1978 | Perceval le Gallois as Perceval |
| 1978 | Violette Nozière as Camus, student |
| 1978 | En répétant Perceval |
| 1976 | Vincent mit l'âne dans un pré (et s'en vint dans l'autre) as Vincent Vergne |
| 1976 | Les Écrans déchirés as Fabrice |
| 1975 | Né as Self |
| 1974 | Ahlaksız Öyküler as André - Story 1 |
| 1970 | Claire'in Dizi as Vincent |
| 1969 | Tout peut arriver as Fabrice |
| Anne et François as François Mitterrand |
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